Incidence and Survival Trends of Cervical Cancer in Khon Kaen, Thailand

To evaluate and report the incidence and survival trends of cervical cancer in Khon Kaen, Thailand, during 1991-2020.

A retrospective study was conducted by using the electronic cancer registry database of Khon Kaen province population. Joinpoint regression model was used to analyze the Age-Standardized Incidence Rate (ASR) and the incidence trend graph was built. Overall Observed Survival (OS) was analyzed by Kaplan Meier method and the survival trend graph was built similarly.

During 1991-2020, 3,071 cervical cancer patients were found in Khon Kaen. Their mean age was 51.7 year-old. The ASR had decreased from 13.51 (95%CI: 10.67-16.35) per 100,000 women-year in 1991 to 7.63 (95%CI: 5.93-9.33) per 100,000 women-year in 2020. This trend was consistent with the country's and international trends. The highest incidence was found in 1993, which was 17.73 (95%CI: 14.65-20.81), and the lowest incidence was found in 2016, which was 5.7 (95%CI: 4.30-7.10) per 100,000 women-year. However, the 5-year OS was 48.37% (95%CI: 46.49-50.22), which was a constant trend. At the beginning in 1991-1995, the OS was 40.31% (95%CI: 35.43-45.12), and at the end in 2016-2020, the OS was 40.46% (95%CI: 34.59-46.23). These were very similar.

In Khon Kaen, Thailand, during 1991-2020, the cervical cancer incidence (ASR) trend was decreasing, while the cervical cancer survival (OS) trend was constant. WHO elimination of cervical cancer initiative target should be reached by 2030.