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Updated: May 9, 2025

3D Imaging of Soft-Tissue Samples using an X-ray Specific Staining Method and Nanoscopic Computed Tomography
Published on: October 24, 2019
The Transition from Refraction to Ultra-Small-Angle X-ray Scattering (USAXS) in a Laboratory Phase-Based X-Ray
Michela Esposito1, Lorenzo Massimi1, Ian Buchanan1
1Department of Medical Physics and Biomedical Engineering, University College London, Gower St, London WC1E 6BT, United Kingdom.
Abstract:
We report on a laboratory-based x-ray microscope allowing for phase-contrast imaging of soft tissue samples. The used beam tracking approach allows retrieval of Ultra-Small-Angle X-ray Scattering (USAXS) or dark field alongside attenuation and differential phase. We show the dependence of the refraction and dark field signal on the size of the imaged features. The application of the technique to a biological sample is also demonstrated.

