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Diaphragmatic pressures: transvenous vs. direct phrenic nerve stimulation
Journal of Applied Physiology (Bethesda, Md. : 1985)
|July 1, 1985
Summary
Direct and transvenous phrenic nerve stimulation methods reliably measure diaphragmatic force over time. Transvenous stimulation is a viable alternative to direct stimulation for assessing diaphragmatic strength.
Area of Science:
- Physiology
- Respiratory Mechanics
Background:
- Assessing diaphragmatic strength is crucial for understanding respiratory function.
- Evaluating the reliability and variability of measurement techniques is essential for clinical application.
Purpose of the Study:
- To assess the inherent variability of diaphragmatic force measurement techniques over a 5-hour period.
- To compare the efficacy of direct phrenic nerve stimulation (DPNS) and transvenous phrenic nerve stimulation (TPNS).
Main Methods:
- Diaphragmatic force was measured in five anesthetized dogs over 5 hours.
- Transdiaphragmatic pressure (Pdi) was recorded during phrenic nerve stimulation (120 Hz, 0.2-ms duration) using both DPNS and TPNS at functional residual capacity.
Main Results:
- No significant changes in diaphragmatic force measurements were observed over the 5-hour study period (P > 0.50).
- A strong positive correlation (r = 0.94, P < 0.001) was found between Pdi values obtained by TPNS and DPNS.
Conclusions:
- Both DPNS and TPNS are reliable methods for evaluating diaphragmatic strength over extended periods.
- TPNS can be effectively used as an alternative to DPNS for assessing diaphragmatic strength.