Transcatheter arterial chemoembolization for lung malignant tumors

Area of Science:

• Interventional Radiology
• Oncology
• Vascular Surgery

Background:

• Transcatheter arterial chemoembolization (TACE) aims to increase local chemotherapy concentration and tumor vascularity control.
• Lung cancer treatment strategies are evolving, with a focus on minimally invasive approaches.
• Understanding tumor blood supply is crucial for effective locoregional therapies.

Purpose of the Study:

• To review the research progression of blood supply to lung cancer.
• To discuss pulmonary artery chemoembolization (PACE) and bronchial artery chemoembolization (BACE) for lung cancer.
• To explore future directions for TACE in lung cancer management.

Main Methods:

• Review of existing literature on TACE for lung cancer.
• Discussion of PACE and BACE techniques, indications, contraindications, and complications.
• Analysis of challenges in percutaneous vascular intervention for lung cancer.

Main Results:

• TACE can enhance drug delivery and tumor vascular occlusion.
• PACE and BACE present distinct approaches with specific applications in lung cancer.
• Key challenges include identifying the precise tumor blood supply and the need for high-quality controlled studies.

Conclusions:

• TACE, including PACE and BACE, holds promise for lung cancer treatment.
• Further research is needed to optimize indications and establish best practices.
• This review provides a reference for vascular interventional radiologists managing lung cancer.