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Related Concept Videos

Base Excision Repair01:54

Base Excision Repair

One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
The first step of...
Long-patch Base Excision Repair01:02

Long-patch Base Excision Repair

Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are:
Base Excision Repair01:54

Base Excision Repair

One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
The first step of...

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Distal Biceps Tendon Repair Using a Unicortical Button.

Gustavo Barrazueta1, Hisham Awan1, Gregory Cvetanovich1

  • 1The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.

Video Journal of Sports Medicine
|May 1, 2025
PubMed
Summary

This study reviews the unicortical button technique for distal biceps tendon repair, showing it offers strength equivalent to bicortical buttons with potential benefits like reduced nerve injury risk. This method provides a safe and effective option for restoring elbow flexion and supination strength.

Keywords:
bicepsbiceps tendon repairdistal biceps tendonunicortical button

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Area of Science:

  • Orthopedic Surgery
  • Sports Medicine
  • Musculoskeletal Research

Background:

  • Distal biceps tendon ruptures commonly affect middle-aged men, causing significant loss of elbow flexion (30%) and supination (40%) strength.
  • Surgical repair is indicated for complete ruptures or failed conservative treatment of partial tears, aiming to restore function.
  • Various fixation methods exist, including bicortical buttons, transosseous tunnels, suture anchors, and interference screws.

Purpose of the Study:

  • To review the technique and outcomes of distal biceps tendon repair using a unicortical button fixation method.
  • To compare the efficacy and safety of unicortical button fixation with other established techniques.

Main Methods:

  • A single-incision technique is employed, utilizing a transverse incision distal to the elbow flexion crease.
  • Onlay fixation of the distal biceps tendon to the radial tuberosity is achieved with a unicortical button.
  • Postoperative protocols are surgeon-dependent but align with standard practices for tendon repair.

Main Results:

  • Primary repair of distal biceps tendon ruptures yields promising outcomes, with good to excellent patient-reported and objective results.
  • Unicortical button fixation demonstrates statistically equivalent cyclic loading and load-to-failure values compared to bicortical button fixation.
  • This equivalence suggests comparable strength to bicortical buttons, which are known to be stiffer than other methods.

Conclusions:

  • The unicortical button technique offers a strong fixation for distal biceps tendon repairs, comparable to bicortical buttons.
  • Potential advantages include a smaller footprint on the radial tuberosity, possibly reducing heterotopic ossification and risk of posterior interosseous nerve injury.
  • This method provides a safe and effective approach for anatomical repair and restoration of elbow function.