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[Food protein-induced enterocolitis syndrome]
Zsuzsa Andrea Domokos1, Kirsten Skamstrup Hansen2, Lene Heise Garvey1
1Klinik for Allergi, Afdeling for Allergi, Hud og Kønssygdomme, Københavns Universitetshospital - Herlev og Gentofte Hospital.
Ugeskrift for Laeger
|May 1, 2025
Summary
Food protein-induced enterocolitis syndrome (FPIES), a non-IgE hypersensitivity, can affect adults. This case report highlights FPIES as a crucial diagnosis in adults experiencing gastrointestinal distress after food ingestion.
Area of Science:
- Gastroenterology
- Allergy and Immunology
Background:
- Food protein-induced enterocolitis syndrome (FPIES) is typically diagnosed in infants.
- It is characterized as a non-immunoglobulin E (IgE)-mediated hypersensitivity reaction to food proteins.
Purpose of the Study:
- To report two adult cases of FPIES.
- To emphasize that FPIES should be considered in adult patients presenting with symptoms suggestive of food allergy.
Main Methods:
- Case report detailing clinical presentation of two adult women.
- Diagnostic evaluation included clinical history and exclusion of other allergic conditions through allergy testing.
Main Results:
- Both patients experienced recurrent severe vomiting and diarrhea hours after consuming mussels.
- Diagnosis of FPIES was established based on clinical history and negative allergy tests.
Conclusions:
- FPIES can manifest in adult patients.
- FPIES is an important differential diagnosis for adults with suspected food allergies and gastrointestinal symptoms.
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