Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Overview of Cell Death

Overview of Cell Death

Cell death is an essential process where the body gets rid of old or damaged cells. Cell proliferation and death need to be balanced, as an imbalance between the two may lead to cancer or autoimmune diseases.
Cell death was observed in the early 19th century, but there was no experimental evidence to prove it. In 1842, Carl Vogt first discovered cell death in a metamorphic toad; however, it was not termed ‘cell death.’ Scientists discovered different cell death pathways only in the 20th century...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Circulating Short-Chain Fatty Acid Profile Predicts Functional Outcome After Moderate-to-Severe Traumatic Brain Injury.

Critical care explorations·2026

Same author

PCSK9 in Brain Health and Disease: Liver-Vascular-Brain Interactions in Aging and Disease.

Aging and disease·2026

Same author

Largest Year-on-Year Decline in Deceased Donation in United States History.

Clinical transplantation·2026

Same author

Arrayed dual-gRNA CRISPR screening platform for <i>C9orf72</i> repeat expansion excision in patient iPSCs.

Molecular therapy. Advances·2026

Same author

Advances in hibernation research: Implications for neurological disease and recovery.

Experimental neurology·2026

Same author

Changes in Organ Donation After Circulatory Death in the United States.

JAMA·2026

Same journal

Erratum for the Research Article "Detecting supramolecular organic nanoparticles during heat wave".

Science (New York, N.Y.)·2026

Same journal

Local signals, systemic decline.

Science (New York, N.Y.)·2026

Same journal

The mechanics of liver regeneration.

Science (New York, N.Y.)·2026

Same journal

Computing in a memory with physics.

Science (New York, N.Y.)·2026

Same journal

Retraction.

Science (New York, N.Y.)·2026

Same journal

Making time.

Science (New York, N.Y.)·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 9, 2026

Pre-clinical Model of Cardiac Donation after Circulatory Death

Pre-clinical Model of Cardiac Donation after Circulatory Death

Published on: August 2, 2019

Discovery research in physiologically maintained deceased.

Douglas B Pet^1,2, Brendan Parent³, Neel S Singhal^1,2

¹Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.

Science (New York, N.Y.)

|May 1, 2025

Summary

This summary is machine-generated.

Research using deceased individuals is expanding, necessitating continuous ethical examination. Ensuring ethical practices is crucial for advancing scientific understanding from human remains.

More Related Videos

Study of Experimental Organ Donation Models for Lung Transplantation

Study of Experimental Organ Donation Models for Lung Transplantation

Published on: March 15, 2024

Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death

Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death

Published on: October 18, 2024

Related Experiment Videos

Last Updated: May 9, 2026

Pre-clinical Model of Cardiac Donation after Circulatory Death

Pre-clinical Model of Cardiac Donation after Circulatory Death

Published on: August 2, 2019

Study of Experimental Organ Donation Models for Lung Transplantation

Study of Experimental Organ Donation Models for Lung Transplantation

Published on: March 15, 2024

Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death

Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death

Published on: October 18, 2024

Area of Science:

Bioethics
Medical Research Ethics

Background:

Research utilizing deceased human bodies offers unique scientific insights.
There is a growing need for ethical frameworks to govern research on human remains.

Purpose of the Study:

To highlight the necessity of ongoing ethical inquiry in research involving deceased humans.
To underscore the importance of ethical considerations in expanding research opportunities.

Main Methods:

This study is a conceptual analysis and ethical review.
It synthesizes current ethical guidelines and debates in human body research.

Main Results:

Expanded research opportunities necessitate a proactive ethical approach.
Existing ethical frameworks may require updates to address novel research methods.

Conclusions:

Continuous ethical deliberation is essential for responsible research on deceased individuals.
Adapting ethical guidelines ensures scientific progress aligns with societal values.