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Updated: May 7, 2026

Template Directed Synthesis of Plasmonic Gold Nanotubes with Tunable IR Absorbance

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Ultrasensitive Ultraviolet Chiral Plasmonic Biosensor Based on Passivated Al Shells.

Shanshan Huang¹, Siyi Wang¹, Xiu Yang¹

¹College of Physics, Sichuan University, Chengdu, Sichuan 610065, China.

ACS Applied Materials & Interfaces

|May 1, 2025

Summary

This summary is machine-generated.

This study introduces an ultrasensitive ultraviolet chiral plasmonic biosensor (CPB) using aluminum chiral shells (ACSs). The novel biosensor significantly enhances detection sensitivity for chiral biomolecules, setting a new record in the field.

Keywords:

chiral biosensor chiral field chiroptical effect glancing angle deposition microsphere lithography ultraviolet chiral metamaterials

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Area of Science:

Plasmonics and Nanophotonics
Chiroptical Spectroscopy
Biosensing Technologies

Background:

Chiroptical spectroscopy is vital for determining biomolecular stereochemistry in bioscience and medicine.
Weak chiroptical effects of natural chiral molecules limit current detection sensitivity.

Purpose of the Study:

To develop an ultrasensitive ultraviolet chiral plasmonic biosensor (CPB).
To overcome the challenge of low detection sensitivity in chiroptical sensing of biomolecules.

Main Methods:

Fabrication of a self-assembled metasurface using passivated aluminum chiral shells (ACSs).
Optimization of ACS geometry and size to create a uniform superchiral field.
Excitation of abundant surface lattice resonance (SLR) modes in the ultraviolet waveband.

Main Results:

Achieved enhanced interaction with chiral biomolecules due to the superchiral field.
Narrowed chiroptical resonance peaks and improved sensor pointer identifiability via SLR modes.
Demonstrated a notable peak shift in g-factor maxima correlating with biomolecule structure and concentration, achieving record chiral sensor parameter U values.

Conclusions:

The developed ultraviolet CPB based on ACSs offers unprecedented sensitivity for chiral biomolecule detection.
The findings establish a new benchmark for chiral plasmonic biosensors, with potential applications in advanced diagnostics.