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Electromagnetic fields regulate iron metabolism: From mechanisms to applications.
Shenghang Wang1, Jiancheng Yang2, Chenxiao Zhen3
1Department of Spine Surgery, People's Hospital of Longhua, Shenzhen, China; Research & Development Institute of Northwestern Polytechnical University in Shenzhen, Shenzhen, China.
Journal of Advanced Research
|May 1, 2025
Summary
Electromagnetic fields (EMFs) significantly alter iron metabolism through biophysical mechanisms. This review explores EMFs
Area of Science:
- Biophysics
- Biomedical Science
- Physical Therapy
Background:
- Electromagnetic fields (EMFs) are utilized in physical therapy and biomedicine.
- Iron is crucial for physiological processes; its metabolic imbalances are linked to diseases.
- EMF exposure demonstrably alters systemic and cellular iron metabolism.
Purpose of the Study:
- To review evidence on EMFs regulating iron metabolism.
- To elucidate potential biophysical mechanisms involved.
- To expand understanding and applications of EMFs in biomedicine.
Main Methods:
- Synthesis of existing research findings.
- Hypothesis formulation on biophysical mechanisms.
- Review of EMF effects on iron metabolism and related diseases.
Main Results:
- EMF regulation of iron metabolism involves electromagnetic properties of iron-containing biomolecules and tissues.
- Mechanisms include modulation of membrane function, ion channels, and reactive oxygen species (ROS).
- EMF effects on iron metabolism are linked to immunoregulation, cardiovascular, neurological, orthopedic, and metabolic diseases, as well as liver injury and cancer.
Conclusions:
- EMFs present a novel therapeutic approach by modulating iron metabolism.
- Understanding these biophysical interactions can lead to new biomedical applications.
- Further research is warranted to fully explore the therapeutic potential and safety of EMFs in iron-related conditions.
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