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Natural Products as Timeless Remedies - Unlocking Nature's Treasure Trove
Tamara Balsiger1, Robin Teufel2, Eliane Garo3
1Department of Pharmaceutical Sciences, University of Basel, CH-4056 Basel. tamara.balsiger@unibas.ch.
Abstract:
Natural products are an essential source of medicines, accounting for a large proportion of approved drugs nowadays. However, the isolation of active natural products from complex extracts is challenging. To address this bottleneck, a drug discovery strategy was developed in our lab, that combines the screening of an in-house crude plant extract library of more than 2,500 samples with an HPLC-based activity profiling approach. This workflow is used routinely in our group and was successfully applied to numerous natural product drug discovery projects.
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