Determination of trace bisphenols in milk based on AMA/DVB@GO@UiO-66-NH2 dispersive micro solid-phase extraction
Weixia Li1, Jiacheng Lei2, Tiancheng He2
1College of Quality and Standardization, China, Jiliang University, Hangzhou, 310018, China. weixia@cjlu.edu.cnb.
Abstract:
A novel Zr-based metal-organic framework (MOF) functionalized with graphene oxide-coated allylmethacrylate-divinylbenzene microspheres (AMA/DVB@GO), termed AMA/DVB@GO@UiO-66-NH2 was designed. The composite exhibits great adsorption capacity and selectivity for bisphenols (BPs), driven by synergistic interactions, including hydrophobic, π-π, and hydrogen bonding. We optimized conditions to establish an efficient dispersive micro-solid phase extraction procedure coupled with high-performance liquid chromatography (d-μSPE-HPLC) for extracting BPs from milk samples, using the AMA/DVB@GO@UiO-66-NH2 composite. The method achieved recoveries ranging from 84.0 to 106.6%, with relative standard deviations below 6.9% and detection limits between 0.17 and 0.67 μg/L. This study introduced a novel, hydrophilic, and stable AMA/DVB@GO@UiO-66-NH2 composite, offering a promising material for the selective enrichment and detection of BPs in food analysis.
