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[The venous-arteriolar reflex].

B Krahenbuhl, O Bongard

    Journal Des Maladies Vasculaires
    |January 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Cutaneous blood flow and transcutaneous pO2 measurements reveal distinct circulatory patterns in severe arterial insufficiency. In ischemic patients, blood flow and oxygenation correlations differ from healthy individuals, suggesting altered nutritional circulation.

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    Area of Science:

    • Vascular Physiology
    • Dermatology
    • Clinical Medicine

    Background:

    • Severe arterial insufficiency significantly impairs lower limb circulation.
    • Assessing cutaneous blood flow and tissue oxygenation is crucial for diagnosis and management.
    • Understanding the relationship between blood flow and oxygenation in ischemic conditions is vital.

    Purpose of the Study:

    • To simultaneously measure cutaneous blood flow and transcutaneous pO2 in the foot.
    • To compare these measurements between healthy subjects and patients with severe arterial insufficiency.
    • To investigate the impact of body position on these circulatory parameters.

    Main Methods:

    • Simultaneous measurement of cutaneous blood flow using Xenon clearance.
    • Simultaneous measurement of transcutaneous oxygen pressure (tc pO2).

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  • Measurements were taken on the foot in both lying and sitting positions.

    • Main Results:

    • Cutaneous blood flow decreased in the sitting position for both groups.
    • Transcutaneous pO2 increased in the sitting position, particularly in patients with low baseline tc pO2.
    • A positive correlation between blood flow and tc pO2 was observed in normal subjects but not in ischemic patients.

    Conclusions:

    • Xenon clearance may reflect total cutaneous blood flow, while tc pO2 indicates nutritional circulation.
    • The lack of correlation in ischemic patients suggests impaired microcirculation and altered tissue perfusion.
    • Sitting position may abolish local vasoregulation, leading to increased tc pO2, especially in severe ischemia.