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Updated: Jul 16, 2026

Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19
Published on: May 25, 2022
Incidence and prognosis of otitis media with effusion in COVID-19 patients a comparative case-control analysis
Qian Yu1, Yuedong Zhang1, Huina Lu2
1Department of Otorhinolaryngology-Head and Neck Surgery, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.
Objective:
To investigate the association between SARS-CoV-2 and secretory otitis media (OME), evaluating the presence of the virus in middle ear fluid (MEF) and its impact on OME incidence and patient outcomes.
Methods:
A case-control study was conducted with COVID-19 patients (n = 86) and control subjects (n = 20). OME incidence was compared across three time periods. Recovery rates, recurrence rates, catheterization rates, Eustachian Tube Dysfunction Questionnaire-7 (ETDQ-7) scores, as well as audiometry results were analyzed.
Results:
The detection of SARS-CoV-2 in MEF samples showed a similar duration compared to nasal swabs (28.65 ± 8.99 vs 27.18 ± 7.99 days). There was a significant increase in OME incidence following COVID-19 infection, particularly during the '22-'23 period (P < 0.05). No significant differences were observed in terms of recovery rates, recurrence rates or catheterization rates among groups (P > 0.05). ETDQ-7 scores remained unchanged after treatment intervention (P > 0.05). Statistically significant differences were found for air conduction threshold and air-bone gap measurements (P < 0.05).
Conclusion:
The presence of SARS-CoV-2 in MEF is associated with an elevated risk of developing OME but has minimal impact on the prognosis of this condition.
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