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Potential of boron neutron capture therapy (BNCT) for epithelioid sarcoma
Takuya Fujimoto1, Tooru Andoh2, Tamotsu Sudo3
1Department of Orthopaedic Surgery, Hyogo Cancer Center, Akashi, 673-8558, Japan.
Abstract:
Epithelioid sarcoma (ES) is a very rare malignant tumor with few effective treatments other than surgical resection. In this study, the efficacy of BNCT for ES was examined using human ES-derived VA-ES-BJ cell-bearing nude mice. Only tumors in the BNCT group injected with p-borono-L-phenylalanine-fructose complex and irradiated with neutrons were destroyed. This study suggests the potential of BNCT as a new option for the treatment of human ES.

