Related Experiment Video
Updated: May 9, 2025
Patient Directed Recording of a Bipolar Three-Lead Electrocardiogram using a Smartwatch with ECG Function
Published on: December 11, 2019
Correlation between mobile and 12-lead ECG among patients loading with intravenous sotalol: A PEAKS substudy
Benjamin A Steinberg1,2,3, Suneet Mittal4, Richard Holubkov5
1Department of Medicine, Denver Health Medical Center, Denver, Colorado.
Background:
Electrocardiographic monitoring is performed during sotalol loading, primarily to assess QTc. Continuous telemetry increases resource utilization, generating interest in streamlining QTc monitoring through mobile technologies.
Objective:
Assess feasibility and outcomes of mobile electrocardiogram (ECG) monitoring during intravenous sotalol loading.
Methods:
In a substudy of the PEAKS (Prospective Evaluation Analysis and Kinetics of IV Sotalol) registry, AliveCor 6L mobile ECGs were recorded during intravenous sotalol loading, concomitantly with standard 12-lead ECGs. We calculated the correlation of heart rate and QTc between them.
Results:
Overall, 77 patients were included: the median age was 68 years (interquartile range 63-73 years) and 20% were female. A total of 227 mobile recordings were performed within 30 minutes of 12-lead ECG, including baseline (8%), during infusion (54%), during oral dosing (35%), and during follow-up (0.4%). Half (51%) of 12-lead tracings were in atrial tachycardia (AT)/atrial fibrillation (AF), with a 93% correlation with automated mobile diagnostics. No mobile QTc values were available for recordings in AT/AF. The overall correlation between 12-lead ECG and mobile ECG was good for continuous heart rate (R > 0.8) but was poor for continuous QTc (R = 0.24). Most physiologic QTc values from the mobile ECGs were within 10% of the adjudicated 12-lead values (83%), with 53% within 5%. There were few false negative values for QTc >500 ms by mobile ECG (n = 2 of 58 [3.4%]).
Conclusion:
Mobile ECGs can be performed during sotalol loading but are limited by the absence of QTc in AT/AF. While QTc values from automated mobile 6-lead ECGs appeared to detect cases of QTc prolongation in sinus rhythm, additional data are needed prior to use for routine clinical monitoring.
Clinicaltrialsgov Id:
NCT05247320.
More Related Videos
Related Concept Videos
01:29Electrocardiogram
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
01:24Correlation between ECG and Cardiac Cycle
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
01:28Electrocardiogram Fundamentals
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
01:30Pulse rhythm
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
01:24ECG Interpretation of Rhythms
Components of the Electrocardiogram
The primary components of a normal ECG waveform in Normal sinus rhythm(NSR) include the P wave, PR interval, QRS complex, ST segment, T wave, and occasionally a U wave.
ECG waveforms are divided by vertical and horizontal lines at standard intervals.
The horizontal axis measures time and rate, and the vertical axis measures amplitude or voltage....
01:16ECG Interpretation of Arrhythmias I: Sinus Arrhythmias
Types of Arrhythmias
Sinus Node Arrhythmias
Sinus Bradycardia: Originating from the sinoatrial (SA) node, sinus bradycardia involves slower impulses, resulting in a heart rate of less than 60 beats per minute (bpm). Causes include sleep, vagal stimulation, beta-blockers, hypothyroidism,...