Related Experiment Video
Updated: May 9, 2025

Hydrogen Production and Utilization in a Membrane Reactor
Published on: March 10, 2023
Kinetic study on the hydrogenation of dimethyl succinate to γ-butyrolactone
Chengzhe Du1, Chenghao Zhao2, Huixia Ma2
1State Key Laboratory of Multiphase Complex Systems, Institute of Process Engineering, Chinese Academy of Sciences Beijing 100190 China czdu@ipe.ac.cn.
Abstract:
The hydrogenation of dimethyl succinate (DMS) to γ-butyrolactone (GBL) is crucial in producing high-value chemicals for pharmaceuticals, agrochemicals, and battery electrolytes. This study utilized a self-developed copper-based catalyst and a micro-fixed bed reactor to systematically investigate the effects of temperature, pressure, and the hydrogen-to-ester ratio on reaction performance. An intrinsic kinetic model was developed based on experimental data, with reaction rate constants and activation energies determined through standard regression techniques. The model correlated well with observed data, providing insights into reaction kinetics. Validation against experimental data indicated fair agreement across various conditions. Sensitivity analysis confirmed the model's robustness, making it useful for process optimization. This kinetic analysis offers insights to enhance the efficiency and cost-effectiveness of industrial GBL production, aiming to improve overall process yield and efficiency.
More Related Videos
05:34Efficient Synthesis of Polyfunctionalized Benzenes in Water via Persulfate-promoted Benzannulation of α,β-Unsaturated Compounds and Alkynes
Published on: December 16, 2019
08:56Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
Published on: November 30, 2022
Related Concept Videos
Electrophilic Addition of HX to 1,3-Butadiene: Thermodynamic vs Kinetic Control
Regioselectivity and Stereochemistry of Acid-Catalyzed Hydration
Reduction of Alkenes: Catalytic Hydrogenation
Metals like palladium, platinum, and nickel are commonly used in their solid forms — fine powder on an inert surface. As these catalysts remain insoluble in the reaction mixture, they are referred to as heterogeneous catalysts.
The hydrogenation process takes place on the...
Reduction of Alkenes: Asymmetric Catalytic Hydrogenation
The metal catalyst used can be either heterogeneous or homogeneous. When hydrogenation of an alkene generates a chiral center, a pair of enantiomeric products is expected to form. However, an enantiomeric excess of one of the products can be facilitated using an enantioselective reaction or an...
Hydroboration-Oxidation of Alkenes
Reduction of Benzene to Cyclohexane: Catalytic Hydrogenation