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Surgical Embolectomy for a Clot-in-Transit Located in a Patent Foramen Ovale: A Case Report
Danielle Drew1, Rayhan Karimi2, Charles J Rousseau3
1Clinical, Biomedical, and Educational Research, Edward Via College of Osteopathic Medicine, Spartanburg, USA.
Cureus
|May 5, 2025
Summary
A blood clot traveled through a heart defect (patent foramen ovale) causing a life-threatening blockage in the lungs. Surgical removal was successful, highlighting its benefit over catheter methods in complex cases.
Area of Science:
- Cardiology
- Pulmonary Medicine
- Vascular Surgery
Background:
- Pulmonary embolism (PE) is a critical manifestation of venous thromboembolism, where clots obstruct pulmonary arteries, potentially causing respiratory failure.
- Patent foramen ovale (PFO) is a common heart defect where an opening between atria persists post-birth, sometimes leading to paradoxical embolism.
Observation:
- A 30-year-old female presented with sudden dyspnea and hemodynamic instability.
- Transesophageal echocardiogram revealed a pulmonary embolism crossing a patent foramen ovale.
- The patient experienced significant decompensation upon anesthesia induction.
Findings:
- A pulmonary embolism in transit was identified at the interatrial septum via a PFO.
- Surgical pulmonary embolectomy and PFO closure were performed urgently.
- The case demonstrated a PE-in-transit causing hemodynamic collapse following positive pressure ventilation.
Implications:
- This case underscores the importance of recognizing concurrent PFO and PE.
- Surgical embolectomy proved beneficial in this complex, massive PE with paradoxical embolism.
- Early surgical intervention is critical for patients with massive PE and PFO presenting with hemodynamic compromise.
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