Related Experiment Video
Updated: Jul 1, 2026

Setting Limits on Supersymmetry Using Simplified Models
Published on: November 15, 2013
An elementary derivation of the "|Δμ| big is good" rule and its implications in several reactivity principles
José L Gázquez1, Marco Franco-Pérez1,2
1Universidad Autónoma Metropolitana-Iztapalapa, Departamento de Química, Av. San Rafael Atlixco 186, Ciudad de Mexico 09340, Mexico.
Abstract:
Recently, Miranda-Quintana, Heidar-Zadeh, and Ayers have elaborated a simple proof of the "Δμ big is good" rule for reactions that are dominated by charge transfer, making use of the smooth quadratic interpolation for fractional electron number and the analysis of several derivatives. In this work, we extend this approach, showing that one can derive a direct relationship of the change in the energy as a function of the change in the absolute value of the chemical potential that implies the "Δμ big is good" rule. In addition, we show that this rule plays an important role in the fulfillment of the hard and soft acids and bases (HSAB), the maximum hardness, and the minimum electrophilicity principles, as anticipated intuitively by Parr.
More Related Videos
11:03An Analog Macroscopic Technique for Studying Molecular Hydrodynamic Processes in Dense Gases and Liquids
Published on: December 4, 2017
05:45Capillary Electrophoresis-based Hydrogen/Deuterium Exchange for Conformational Characterization of Proteins with Top-down Mass Spectrometry
Published on: June 8, 2021
Related Concept Videos
The Quantum-Mechanical Model of an Atom
The Pauli Exclusion Principle
Rate-Determining Steps
In a multistep reaction mechanism, one of the elementary steps progresses significantly slower than the others. This slowest step is called the rate-limiting step (or rate-determining step). A reaction cannot proceed faster than its slowest step, and hence, the rate-determining step limits the overall reaction rate.
The concept of rate-determining step can be understood from the analogy of a 4-lane freeway with a short-stretch of traffic-bottleneck caused due to...
Reaction Quotient
Woodward–Hoffmann Selection Rules and Microscopic Reversibility
UV–Vis Spectroscopy: Woodward–Fieser Rules