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Updated: May 9, 2025

Establishment and Characterization of UTI and CAUTI in a Mouse Model
Published on: June 23, 2015
What is chronic urinary tract infection? A systematic review
Janni Søvsø Hjelmager1, Karin Andersen2, Thomas Emil Andersen1,3
1Research Unit of Clinical Microbiology, University of Southern Denmark, Odense, Denmark.
Objective:
To define 'chronic' urinary tract infection (UTI) by reviewing current published research that employs this term.
Methods:
We systematically searched Medline and Embase for studies covering all aspects of human UTI. For comparison, current urological and infectious disease guidelines were also reviewed.
Results:
The electronic search yielded a total of 2175 articles, of which 154 were eventually included for data extraction. Of these, six studies presented a definition of chronic UTI within the text. The definitions were highly incongruent among studies and often identical to the current definition of 'recurrent' UTI.
Conclusion:
Chronic UTI is an undefined term, which has nevertheless been increasingly used in the past 15 years. Chronic UTI does not represent a distinct clinical or microbiological condition that justifies its use as medical diagnosis.
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