Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Proteomics01:33

Proteomics

7.1K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
7.1K
Ribosome Profiling02:24

Ribosome Profiling

3.4K
Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
3.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Moso bamboo encroachment into broadleaved forest increased the relative contribution of bacterial community to heterotrophic nitrification.

Ying yong sheng tai xue bao = The journal of applied ecology·2026
Same author

Plant-derived extracellular vesicles as emerging biotherapeutic agents and delivery vehicles for rheumatoid arthritis: evidence from preclinical models.

Frontiers in immunology·2026
Same author

A Facile and Biocompatible Hydrogel Based on Oxidized <i>Brachybotrys paridiformis</i> Polysaccharide for Enhanced Wound Healing.

ACS omega·2026
Same author

Development of a prediction model for recurrent vertebral fractures in patients two years after vertebral augmentation using noninvasive data: a retrospective study.

BMC musculoskeletal disorders·2025
Same author

FairAlloc: Learning Fair Organ Allocation Policy for Liver Transplant.

Journal of healthcare informatics research·2025
Same author

Selectivity optimization of real-time and continuous sensing of endogenous H<sub>2</sub>S in biological fluids.

Mikrochimica acta·2025
Same journal

Heterojunction-Enhanced Interfacial Evanescent-Tunable Fiber Optic Probe for Amplification-free CRISPR/Cas12a-Based Rapid and Ultrasensitive Detection of MPXV.

Analytical chemistry·2026
Same journal

Tunable Charge Transfer in Europium Metal-Organic Frameworks for Ratiometric Sensing of a Sarin Simulant.

Analytical chemistry·2026
Same journal

A β-Cyclodextrin/Ag<sub>2</sub>O@MWCNT-Based Stochastic Platform for the Simultaneous Molecular Enantiorecognition and Enantioanalysis of Twelve Amino Acids in Biological Matrices.

Analytical chemistry·2026
Same journal

The ACS at 150: The History of Analytical Chemistry Publications and a Century of Progress.

Analytical chemistry·2026
Same journal

Machine Learning-Enabled Image Analysis of Complex Chemical Mixtures: Synthetic Urine Droplets as a Test System.

Analytical chemistry·2026
Same journal

H<sub>2</sub>O<sub>2</sub>/Viscosity Tandem-Locked Fluorescent Probes Based on an In Situ Fluorophore Synthesis Strategy for Colitis Imaging and Diagnosis.

Analytical chemistry·2026
See all related articles

Related Experiment Video

Updated: May 21, 2025

Resolving Affinity Purified Protein Complexes by Blue Native PAGE and Protein Correlation Profiling
09:35

Resolving Affinity Purified Protein Complexes by Blue Native PAGE and Protein Correlation Profiling

Published on: April 1, 2017

13.8K

Protein Profiling by Nanopore-Based Technology.

Funa Meng1, Xin Li1, Na Zou1

  • 1School of Chemistry and Chemical Engineering, Heze University, Shandong 274015, P. R. China.

Analytical Chemistry
|May 6, 2025
PubMed
Summary
This summary is machine-generated.

Nanopore technology enables single-molecule protein analysis, advancing protein identification, quantification, and sequencing. This review highlights recent breakthroughs and future strategies for nanopore-based protein sensing.

More Related Videos

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
10:37

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification

Published on: November 15, 2017

11.9K
Sequencing of mRNA from Whole Blood using Nanopore Sequencing
11:26

Sequencing of mRNA from Whole Blood using Nanopore Sequencing

Published on: June 3, 2019

13.5K

Related Experiment Videos

Last Updated: May 21, 2025

Resolving Affinity Purified Protein Complexes by Blue Native PAGE and Protein Correlation Profiling
09:35

Resolving Affinity Purified Protein Complexes by Blue Native PAGE and Protein Correlation Profiling

Published on: April 1, 2017

13.8K
Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
10:37

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification

Published on: November 15, 2017

11.9K
Sequencing of mRNA from Whole Blood using Nanopore Sequencing
11:26

Sequencing of mRNA from Whole Blood using Nanopore Sequencing

Published on: June 3, 2019

13.5K

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Nanotechnology

Background:

  • Proteins are fundamental to biological processes and disease.
  • Nanopore technology offers single-molecule analysis capabilities.
  • Protein analysis is crucial for understanding biological functions.

Purpose of the Study:

  • To provide an overview of recent advances in nanopore-based protein profiling.
  • To focus on diverse approaches to single-molecule protein sequencing.
  • To discuss challenges and potential solutions in nanopore protein sensing.

Main Methods:

  • Review of current literature on nanopore technology for protein analysis.
  • Focus on identification, quantification, conformation, and interaction studies.
  • Emphasis on various protein sequencing methodologies using nanopores.

Main Results:

  • Nanopore technology has significantly advanced protein identification and detection.
  • Single-molecule protein sequencing is a rapidly developing area.
  • Diverse nanopore approaches enable detailed protein characterization.

Conclusions:

  • Nanopore sensing offers powerful tools for protein analysis at the single-molecule level.
  • Continued advancements in nanopore engineering and data processing are needed.
  • Nanopore technology holds great promise for future protein research and diagnostics.