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Updated: May 11, 2026

High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes
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Published on: March 24, 2015

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Interferon Causes Endothelial Injury in Humans.

Maria M Adeva-Andany1, Lucía Adeva-Contreras2, Carlos Fernandez-Fernandez1

  • 1Department of Internal Medicine, Hospital General Juan Cardona, c/ Pardo Bazán, s/n, Ferrol 15406, Spain.

Current Reviews in Clinical and Experimental Pharmacology
|May 6, 2025
PubMed
Summary

Interferon therapy and upregulation can cause small blood vessel damage through complement activation. Complement blockade with eculizumab shows promise in treating interferon-induced endothelial injury.

Keywords:
Thrombotic microangiopathyatrophic papulosiscomplement.dermatomyositislupus erythematosusmonoclonal gammopathysystemic capillary leak syndrome

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