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Updated: May 9, 2025
Author Spotlight: Insights into the Techniques and Findings of Recent Advancements in Epilepsy Research
Published on: October 13, 2023
Visualizing ozone fluctuations employing a fluorescent probe in stimulated-epilepsy cell models
Jian Zhang1,2, Yu Duan1, Chang Liu1
1College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Provincial Key Laboratory of Clean Production of Fine Chemicals, Shandong Normal University, Jinan 250014, P. R. China. wangxu@sdnu.edu.cn.
Abstract:
BID-Ozo, a mitochondrial-targeted fluorescence probe to detect endogenous ozone (O3) was developed. A significant increase in intracellular O3 was observed in PC12 cells stimulated with high concentrations of glutamate (Glu), which is used to model epilepsy.
