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Intraindividual Comparison of Ultrafast versus Standard Two-dimensional Dynamic Contrast-enhanced Breast MRI
Maike Bode1, Stephanie Morscheid1, Elene Iordanishvili1
1Department of Diagnostic and Interventional Radiology, University Hospital Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany.
Radiology
|May 6, 2025
Summary
Ultrafast breast MRI did not improve cancer detection or classification compared to standard dynamic contrast-enhanced (DCE) MRI. Despite reducing background parenchymal enhancement (BPE), ultrafast MRI resulted in lower lesion conspicuity and image quality.
Area of Science:
- Radiology
- Medical Imaging
- Oncology
Background:
- Ultrafast breast MRI aims to improve cancer conspicuity by reducing background parenchymal enhancement (BPE) and enhance lesion classification.
- Previous studies integrated ultrafast MRI into standard dynamic contrast-enhanced (DCE) MRI protocols, potentially affecting results.
Purpose of the Study:
- To conduct an intraindividual comparison of ultrafast MRI versus standard DCE MRI for lesion conspicuity and classification.
- To evaluate both methods including the early postcontrast phase for diagnostic assessment.
Main Methods:
- Retrospective analysis of 31 women undergoing both DCE MRI and ultrafast MRI within 2 days.
- Comparison of BPE, image quality, lesion conspicuity, morphology, and kinetic parameters between the two MRI techniques.
Main Results:
- Ultrafast MRI showed lower BPE ratings (2.5 vs 3.3) but also reduced lesion conspicuity (3.5 vs 4.1) and image quality (2.3 vs 4.1) compared to DCE MRI.
- Lesion morphology was less assessable with ultrafast MRI.
- Kinetic parameters from ultrafast MRI did not improve lesion classification, unlike DCE MRI's wash-in rate and time course pattern.
Conclusions:
- In this cohort, ultrafast MRI led to reduced lesion conspicuity and did not improve the classification of enhancing breast lesions compared to standard DCE MRI.
- Further research is needed to optimize ultrafast MRI techniques for breast cancer assessment.
