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Intertransverse process block: A narrative review
1Department of Anesthesiology and Perioperative Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China.
Journal of Clinical Anesthesia
|May 6, 2025
Summary
Intertransverse process block (ITPB) offers a safe and effective thoracic nerve block for various surgeries and trauma pain. Further research is needed to fully establish its widespread clinical utility and superiority.
Area of Science:
- Anesthesiology
- Pain Management
- Thoracic Surgery
Background:
- Intertransverse process block (ITPB) encompasses novel thoracic paraspinal nerve block techniques.
- These techniques target the retro-superior costotransverse ligament space with variations in needle approach.
- ITPB is recognized for ease of performance and reliable analgesia with reduced complication risks.
Purpose of the Study:
- To review the anatomical basis, mechanism, and clinical applications of ITPB.
- To discuss the shortcomings and future research directions for ITPB.
- To provide insights for multimodal analgesia strategies.
Main Methods:
- Narrative review of existing literature on ITPB.
- Summary of anatomical landmarks and procedural variations.
- Analysis of clinical applications and safety profiles.
Main Results:
- ITPB techniques demonstrate ease of location, rapid execution, and effective pain relief.
- The technique shows potential in reducing risks such as pneumothorax and intraspinal injection.
- Current evidence is limited, necessitating further large-scale randomized controlled trials.
Conclusions:
- ITPB is a promising regional anesthesia technique for thoracic and abdominal surgeries, and trauma.
- Further validation through robust clinical trials is essential to confirm its safety and efficacy.
- ITPB has the potential to enhance multimodal analgesia protocols.

