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Feasibility of celiac axis delineation and treatment on combined magnetic resonance imaging and linear accelerator
Sara N Lim1, Yirong Liu1, Anugayathri Jawahar2
1Department of Radiation Oncology, Northwestern University Feinberg School of Medicine, 251 E Huron St, Chicago, IL 60611, USA.
Abstract:
Trials have been performed on irradiating celiac plexus for pancreatic cancer pain management. Images from a combined magnetic resonance imaging and linear accelerator system (MR-linac) for ten patients were assessed for delineation of celiac ganglia, aiming for smaller target volumes and reducing treatment risks versus standard linac-based treatments. MRI-linacs showed superior soft tissue contrast, enabling increased dose to ganglia while irradiating smaller target volumes versus regular linacs (median: 0.8 cm3 vs. 32.2 cm3, p < 0.05 for ten pairs of plans). While further studies are needed, MR-linac treatments could improve targeting precision, minimize dose to organs-at-risk and enhance effectiveness in palliative care.
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Computed Tomography (CT) scan:
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