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Liquid Chromatography-Mass Spectrometry Metabolomic Analysis of Terminalia ferdinandiana Exell. Fruit Extracts That

Ian Edwin Cock1, Benjamin Matthews2, Adriaan Erasmus Basson3

  • 1Centre for Planetary Health and Food Security, Griffith University, Brisbane 4222, Australia.

Molecules (Basel, Switzerland)
|May 7, 2025
PubMed
Summary

Methanolic and aqueous extracts from T. ferdinandiana fruits show potent activity against HIV-1 replication. These natural compounds inhibit viral infection, reverse transcriptase, and protease, offering a promising avenue for new anti-HIV-1 therapies.

Keywords:
CombretaceaeHIV-1 proteaseHIV-1 replication cycleHIV-1 reverse transcriptaseKakadu plumflavonoidmetabolomics profilingstilbenetanninviral cell entry assay

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