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Related Concept Videos

Ultrasonography01:17

Ultrasonography

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Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called...
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Sound Waves01:01

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Sound waves can be thought of as fluctuations in the pressure of a medium through which they propagate. Since the pressure also makes the medium's particles vibrate along its direction of motion, the waves can be modeled as the displacement of the medium's particles from their mean position.
Sound waves are longitudinal in most fluids because fluids cannot sustain any lateral pressure. In solids, however, shear forces help in propagating the disturbance in the lateral direction as well....
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Echo01:06

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The human ear cannot distinguish between two sources of sound if they happen to reach within a specific time interval, typically 0.1 seconds apart. More than this, and they are perceived as separate sources.
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Tissue Homogenization and Cell Lysis01:32

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Tissue homogenization involves disintegrating tissue architecture and lysing cells, and is an early step in isolating and analyzing cellular components. The method used for homogenization depends on the sample type, the amount of sample available, the analyte to be obtained, and the sensitivity of the method. These methods are broadly classified as mechanical and non-mechanical methods.
Mechanical methods of tissue homogenization
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Sound Waves: Interference00:53

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Sound waves can be modeled either as longitudinal waves, wherein the molecules of the medium oscillate around an equilibrium position, or as pressure waves. When two identical waves from the same source superimpose on each other, the combination of two crests or two troughs results in amplitude reinforcement known as constructive interference. If two identical waves, that are initially in phase, become out of phase because of different path lengths, the combination of crests with troughs...
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Replicating a tissue with sound waves.

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Ultrasound waves offer a novel way to print medical implants directly inside the body. This breakthrough technology allows for on-demand fabrication, potentially revolutionizing personalized medicine and surgical procedures.

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Area of Science:

  • Biomedical Engineering
  • Medical Imaging
  • Materials Science

Background:

  • Current methods for implant fabrication and placement can be invasive and time-consuming.
  • The need for in-situ, patient-specific medical device manufacturing is growing.

Purpose of the Study:

  • To investigate the feasibility of using focused ultrasound waves for in-vivo 3D printing of medical implants.
  • To demonstrate the capability of ultrasound to penetrate biological tissues for additive manufacturing.

Main Methods:

  • Utilizing high-intensity focused ultrasound (HIFU) to precisely deposit biomaterials at targeted locations within simulated tissue.
  • Developing printable bio-inks compatible with ultrasound-mediated deposition and capable of forming stable structures.

Main Results:

  • Successfully demonstrated ultrasound-guided deposition of materials through several centimeters of tissue-mimicking phantom.
  • Achieved on-demand printing of small, defined structures in-situ, confirming the potential for implant fabrication.

Conclusions:

  • Focused ultrasound waves provide a non-invasive method for delivering and solidifying materials within biological tissues.
  • This technology holds promise for future applications in regenerative medicine and customized implant surgery.