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A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development
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A brief history of the CNS cholinergic transmission

A Claudio Cuello1, Ezio Giacobini2

  • 1Department of Pharmacology & Therapeutics, Faculty of Medicine, McGill University, Montreal, QC, Canada; Department of Pharmacology, Oxford University, Oxford, United Kingdom.

Handbook of Clinical Neurology
|May 8, 2025
PubMed

Keywords:
AcetylcholineAcetylcholine quantal releaseChemical transmissionCholinesterasesElectrical transmissionMuscarineSynaptic vesiclesVagusstoff

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