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Updated: May 17, 2025

Discovery of Driver Genes in Colorectal HT29-derived Cancer Stem-Like Tumorspheres
Published on: July 22, 2020
[Retracted] RNA interference against TRIM29 inhibits migration and invasion of colorectal cancer cells
Weihong Xu1, Bin Xu1, Yiting Yao1
1Department of Clinical Laboratory of Shanghai Tongren Hospital, Shanghai Jiaotong university School of Medicine, Shanghai 200336, P.R. China.
Abstract:
Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the western blotting data featured in Figs. 4C on p. 1415 and 5D on p. 1416 were strikingly similar to data that had already appeared in other articles written by different authors at different research institutes, one of which has been retracted. Owing to the fact that the abovementioned data had already been published prior to the receipt of this article at Oncology Reports, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused. [Oncology Reports 36: 1411‑1418, 2016; DOI: 10.3892/or.2016.4941].
Insights
This study on cancer research has been retracted due to concerns about duplicated western blotting data. The journal retracted the paper after authors failed to provide an explanation for the data similarities.
Area of Science:
- Oncology
- Biomedical Research
- Scientific Publishing Ethics
Background:
- Concerns were raised by a reader regarding the western blotting data presented in the study.
- Similar data had previously appeared in publications from different research institutions, including one retracted paper.
Purpose of the Study:
- To address concerns about potential data duplication and scientific misconduct.
- To ensure the integrity of published research in oncology.
Main Methods:
- Editorial review of submitted data.
- Comparison of western blotting figures (Figs. 4C and 5D) with previously published data.
- Communication with authors to seek clarification.
Main Results:
- Striking similarities were identified between the study's western blotting data and pre-existing published data.
- The authors did not provide a satisfactory explanation or reply to the editorial office regarding the data concerns.
Conclusions:
- The paper has been retracted from Oncology Reports due to concerns of data duplication and lack of author response.
- Retraction upholds the standards of scientific integrity in published oncology research.
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