[Retracted] RNA interference against TRIM29 inhibits migration and invasion of colorectal cancer cells

Weihong Xu1, Bin Xu1, Yiting Yao1

  • 1Department of Clinical Laboratory of Shanghai Tongren Hospital, Shanghai Jiaotong university School of Medicine, Shanghai 200336, P.R. China.

Oncology Reports
|May 9, 2025
PubMed

Insights

This study on cancer research has been retracted due to concerns about duplicated western blotting data. The journal retracted the paper after authors failed to provide an explanation for the data similarities.

Area of Science:

  • Oncology
  • Biomedical Research
  • Scientific Publishing Ethics

Background:

  • Concerns were raised by a reader regarding the western blotting data presented in the study.
  • Similar data had previously appeared in publications from different research institutions, including one retracted paper.

Purpose of the Study:

  • To address concerns about potential data duplication and scientific misconduct.
  • To ensure the integrity of published research in oncology.

Main Methods:

  • Editorial review of submitted data.
  • Comparison of western blotting figures (Figs. 4C and 5D) with previously published data.
  • Communication with authors to seek clarification.

Main Results:

  • Striking similarities were identified between the study's western blotting data and pre-existing published data.
  • The authors did not provide a satisfactory explanation or reply to the editorial office regarding the data concerns.

Conclusions:

  • The paper has been retracted from Oncology Reports due to concerns of data duplication and lack of author response.
  • Retraction upholds the standards of scientific integrity in published oncology research.

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