Towards an official gene nomenclature for Populus trichocarpa

The HUGO Gene Nomenclature Committee (www.genenames.org), which has been naming human genes for over 40 years, has been tasked with establishing an official gene nomenclature system for the black cottonwood tree Populus trichocarpa (Torr. & Gray). Here, we review the factors that must be considered when establishing gene nomenclature guidelines. What makes a good gene symbol, and what lessons can be learned from other nomenclature projects? Are there particular challenges associated with naming genes in poplar species? We look at the published gene symbols for Populus and highlight some issues, e.g., the same symbols being used for different genes, and diverse approaches to naming in gene families. What approaches can we take to resolving such conflicts? Since community adoption is key to the success of any nomenclature initiative, we have surveyed poplar researchers for feedback on draft guidelines and discussed some of the issues raised. Finally, we discuss the sustainability of such infrastructure projects-if we build it, will they come and who will fund the ongoing work?