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Updated: May 7, 2026
Doppler Optical Coherence Tomography of Retinal Circulation
Published on: September 18, 2012
Dual acquisition scheme-based optical coherence tomography 3D angiography
Junxiong Zhou1, Wei Chen1, Jianbo Tang1
1Southern University of Science and Technology, Guangdong Provincial Key Laboratory of Advanced Biomaterials, Department of Biomedical Engineering, Shenzhen, China.
Significance:
Optical coherence tomography angiography (OCTA) is a noninvasive technique dedicated to high-resolution microvasculature imaging. However, the projection artifacts of large pial vessels make it difficult to visualize the underlying microvessels, challenging its 3D vascular imaging ability.
Aim:
We propose a dual acquisition scheme-based 3D OCTA method aimed at simultaneously mitigating projection artifacts and enhancing the detection of capillary networks.
Approach:
In this study, we introduce an approach incorporating a dual data acquisition scheme with optimally oriented flux (OOF) filtering to address this problem. The repeated A-scan acquisition scheme and corresponding data processing algorithm were used to address the projection artifact issue underneath large pial vessels, whereas repeated B-scan acquisition-based data processing was used to image the capillary network.
Results:
With such a processing scheme, the projection artifacts can be effectively suppressed, whereas the high detection sensitivity to small vessels of repeat B-scan OCTA can be preserved, thus enabling high-sensitivity 3D imaging of the cerebral vasculature after OOF filtering.
Conclusions:
The results demonstrate the capability of the proposed method for 3D OCTA imaging, which may play an important role in cerebral microvascular dysfunction-related disease studies.
