Onsite Analysis of Complex Samples Using Miniature Mass Spectrometry With Direct Sampling and Ionization.

Area of Science:

• Analytical Chemistry
• Environmental Science

Background:

• Miniature mass spectrometry (mini-MS) is crucial for onsite analysis of complex samples.
• Effective onsite sampling and ionization are essential for rapid screening in field environments.
• There is a need for direct sampling/ionization methods compatible with mini-MS.

Purpose of the Study:

• To develop a direct sampling/ionization kit for miniature mass spectrometry.
• To enable rapid, onsite analysis of complex raw samples.

Main Methods:

• A direct sampling/ionization kit utilizing a wooden tip or plant tissue was developed.
• The kit was coupled with mini-MS/MS for targeted analyte detection and identification.
• Analytical performance was evaluated using pesticide detection in juice and direct tissue analysis.

Main Results:

• The wooden tip kit successfully sampled and ionized various raw samples (powders, liquids, viscous).
• Excellent sensitivity, reproducibility, and quantitation capacity were achieved for direct pesticide analysis in juice.
• Direct ionization of biological tissue demonstrated a fast, simple, and efficient method.

Conclusions:

• The developed direct sampling/ionization method using a wooden tip is simple, fast, and sensitive.
• This approach is suitable for onsite direct analysis of raw samples in field settings.
• The method enhances the applicability of mini-MS for field-based sample analysis.