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Updated: May 15, 2025

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
Published on: August 20, 2019
Nursing's Role in Advancing Care for Rare Genetic Diseases
Andrew A Dwyer1, Suja Somanadhan2
1William F. Connell School of Nursing, Boston College, Chestnut Hill, MA 20476, USA; P50 Massachusetts General Hospital - Harvard Center for Reproductive Medicine, Boston, MA, USA.
Abstract:
Rare diseases (RDs) are predominantly genetic in etiology and characterized by low frequency and high medical complexity. Although individually infrequent, the cumulative public health impact of ∼7000 RDs is significant, and patients and families experience significant psychosocial burden. Health disparities stem from delays in diagnosis (diagnostic odyssey), difficulty accessing care, and lack of effective treatments. This article provides an overview of rare genetic diseases and highlights exemplar cases demonstrating nursing's role in advancing comprehensive, person-centered care for rare genetic diseases. Resources and recommendations are provided for nurses to enhance quality care for individuals and families living with RDs.
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