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Updated: May 12, 2025

Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction
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Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction

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Molecular glue meets antibody: next-generation antibody-drug conjugates

Yiran Tao1, Ying Lu1, Bin Yu2

  • 1Department of Pulmonary and Critical Care Medicine, Targeted Tracer Research and Development Laboratory, Institute of Respiratory Health, Frontiers Science Center for Disease-Related Molecular Network, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, China.

Trends in Pharmacological Sciences
|May 9, 2025
PubMed

Keywords:
antibody–drug conjugateartificial intelligencemolecular gluemolecular glue–antibody conjugatetargeted protein degradation

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