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Dual pathogenic mechanisms in lysinuric protein intolerance: Interplay between hyperammonemia and cellular metabolic

Keisuke Kakisaka1, Takuro Sato1, Yasunori Wada2

  • 1Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Iwate Medical University, Yahaba, Japan.

Molecular Genetics and Metabolism
|May 11, 2025
PubMed
Abstract

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Keywords:
Amino acid transportAstrocytesLysinuric protein intoleranceReactive oxygen speciesSLC7A7ammonia toxicity