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Surgery scheduling based on large language models.

Fang Wan1, Tao Wang1, Kezhi Wang2

  • 1INSA LYON, Université Lyon2, Université Claude Bernard Lyon1, Université Jean Monnet Saint-Etienne, DISP UR4570, France.

Artificial Intelligence in Medicine
|May 11, 2025
PubMed
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Large Language Models (LLMs) enhance surgery scheduling by acting as evolutionary optimizers. LLM-NSGA significantly improves solutions and optimizes parameters, outperforming traditional methods.

Area of Science:

  • Artificial Intelligence
  • Operations Research
  • Computational Optimization

Background:

  • Traditional multi-objective optimization algorithms (e.g., NSGA-II) often require domain expertise for operator design.
  • Large Language Models (LLMs) show potential across various fields, including complex problem-solving.

Purpose of the Study:

  • To explore the application of LLMs in solving multi-objective combinatorial optimization problems, specifically surgery scheduling.
  • To introduce LLM-NSGA, a novel approach where LLMs function as evolutionary optimizers.

Main Methods:

  • LLMs were employed to perform selection, crossover, and mutation operations within an evolutionary framework (LLM-NSGA).
  • LLM-NSGA was compared against traditional algorithms (NSGA-II, MOEA/D) and another LLM-based method (EoH).
Keywords:
Combinatorial optimizationHyperparameter optimizationLarge language modelsMulti-objectiveSurgery scheduling

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  • LLMs were also utilized for hyperparameter optimization, compared against Bayesian Optimization and Ant Colony Optimization (ACO).
  • Main Results:

    • LLM-NSGA generated high-quality solutions independently from prompts for 40 cases.
    • LLM-NSGA demonstrated superior performance over NSGA-II and MOEA/D as problem size increased, with average improvements of 5.39%, 80%, and 0.42% in three objectives.
    • LLMs reduced hyperparameter optimization runtime by 23.68% and yielded parameters that improved surgery scheduling solutions when validated with NSGA-II.

    Conclusions:

    • LLMs can effectively serve as evolutionary optimizers for complex problems like surgery scheduling.
    • LLM-NSGA offers a promising alternative to traditional methods, achieving better results and improving resource allocation.
    • LLMs efficiently optimize algorithm parameters, enhancing the performance of existing optimization techniques.