Advances in Genetic Testing of Neurologically Abnormal Neonates in the Neonatal Intensive Care Unit

Recent advances in cost and speed with which genome sequencing can be achieved have changed the approach to genetic testing in neonatal intensive care units (NICUs). In this article, we review the impact of these changes on the genetic evaluation of the neurologically abnormal neonate admitted to a NICU and share our center's approach to this important patient population, developed through multidisciplinary collaboration and reflective of a growing body of literature. We emphasize the importance of early identification of treatable disorders and other actionable findings.