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Development of a new self-cleaning denture base material using titanium apatite
Satoshi Komasa1, Yuichiro Tashiro2, Akiko Miyake3
1Department of Oral Health Sciences, Faculty of Health Sciences, Osaka Dental University.
Dental Materials Journal
|May 11, 2025
Summary
This study developed a new denture base material by adding titanium apatite (TiHA) to conventional resin. The new material effectively suppressed bacterial growth without compromising strength, improving denture hygiene for older patients.
Area of Science:
- Biomaterials Science
- Dental Materials
- Polymer Science
Background:
- Denture stomatitis and aspiration pneumonia are significant health concerns for older patients, often linked to contaminated dentures.
- Developing self-cleaning denture base materials is crucial for improving oral health and quality of life in this population.
Purpose of the Study:
- To develop a novel denture base material incorporating titanium apatite (TiHA) into polymethyl methacrylate (PMMA) resin.
- To evaluate the antibacterial properties and mechanical integrity of the TiHA-modified denture base material.
Main Methods:
- Titanium apatite (TiHA) was incorporated at concentrations of 3%, 6%, and 9% into methyl methacrylate (MMA) during PMMA polymerization.
- Surface analysis was performed to confirm TiHA distribution.
- Bacterial growth inhibition and compressive strength were assessed for control (0% TiHA) and experimental groups.
Main Results:
- Surface analysis confirmed the presence and distribution of TiHA crystals on the PMMA surface.
- A dose-dependent suppression of bacterial growth was observed with increasing TiHA concentration.
- No significant reduction in compressive strength was found in the experimental groups compared to the control.
Conclusions:
- Titanium apatite (TiHA) is a promising additive for denture base resins, enhancing resistance to surface contamination and bacterial adhesion.
- The developed TiHA-modified denture base material offers a potential solution for preventing denture-related infections and improving patient quality of life.

