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Published on: August 16, 2018
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[A new triterpenoid from Elephantopus scaber]
Zu-Xiao Ding1, Hong-Xi Xie2, Lin Chen2
1Yunnan Key Laboratory of Pharmacology for Natural Products, School of Pharmacy, Kunming Medical University Kunming 650500, China.
Summary
Researchers identified ten chemical compounds from Elephantopus scaber, including a new triterpene. This study details the isolation and structural identification of these natural products.
Area of Science:
- Natural Product Chemistry
- Phytochemistry
- Organic Chemistry
Context:
- Elephantopus scaber is a medicinal plant with a history of traditional use.
- Investigating the chemical constituents of medicinal plants is crucial for discovering new bioactive compounds.
- The petroleum ether extract of Elephantopus scaber was analyzed to identify its chemical makeup.
Purpose:
- To isolate and identify chemical constituents from the petroleum ether extract of Elephantopus scaber.
- To characterize a novel triterpene and other compounds previously unreported in this plant species.
- To contribute to the phytochemical knowledge base of Elephantopus scaber.
Summary:
- Ten compounds were isolated from the 90% ethanol extract of Elephantopus scaber using various chromatographic techniques.
- Structural elucidation was performed using 1D NMR, 2D NMR, MS, and IR spectral data.
- A new triterpene (compound 1) was identified, along with eight compounds new to this plant and two known compounds (betulinic acid and 3β-hydroxyolean-12-en-28-oic acid).
Impact:
- Expands the known chemical diversity of Elephantopus scaber.
- Provides a foundation for further pharmacological studies on the isolated compounds.
- Highlights the potential of Elephantopus scaber as a source of novel natural products.
