Does a Well-Differentiated Oral Squamous Cell Carcinoma Always Behave Well? A Case Series

Oral squamous cell carcinoma is the sixth most common human cancer and is usually preceded by a premalignant lesion. The patient usually presents it to the clinician at an advanced stage where there are limited treatment options available with declining survival rates. Cancer-deteriorated human lives have prepared the clinicians to take a significant step toward the better survival of patients. Hence, here, we report a case series of oral cancer using some prognostic factors that served in reaching out to conclusion and might favor a diagnostic help to clinicians and pathologists. The final diagnosis for every case was given as well-differentiated squamous cell carcinoma, yet they all exhibited poor prognostic parameters. Predictive markers of oral carcinoma in clinical, surgical, and histopathological fields contribute to their improved status of living. Such parameters, evaluated here in this case series, might lend a helping hand in determining the patient vulnerability toward poor survival and be provided with best treatment interventions.