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Incidence of orbital cellulitis in children: a population-based study
Caroline N Vloka1, Ryan C Summers2, Diana DeSantis3
1University of Colorado School of Medicine, Ophthalmology Department, Aurora, Colorado.
Orbital cellulitis (OC) incidence in children is 3.00/100,000 in Colorado, varying significantly by age, sex, race, and ethnicity. National projections estimate 3.21/100,000, with 2,331 cases annually in the US.
Area of Science:
- Ophthalmology
- Pediatrics
- Epidemiology
Background:
- Orbital cellulitis (OC) is a serious infection requiring prompt diagnosis and treatment.
- Understanding the epidemiology of OC in pediatric populations is crucial for public health initiatives.
Purpose of the Study:
- To determine the incidence of orbital cellulitis (OC) in children in Colorado, stratified by age, sex, race, and ethnicity.
- To project the national incidence rate and disease burden of pediatric OC.
Main Methods:
- Retrospective observational surveillance study of pediatric patients (<18 years) with confirmed OC.
- Data collected in Colorado from January 1, 2018, to December 31, 2022.
- Analysis included calculation of crude rates, age-adjusted incidence rates (ASR), and age-specific incidence rates (ASIR).
Main Results:
- The overall ASR of OC in Colorado was 3.00/100,000 person-years.
- Incidence was highest in five-year-olds (5.97/100,000) and lowest in infants (<1 year) and older adolescents (16-17 years).
- Males, Black/African American children, and non-Hispanic/Latino children exhibited higher OC incidence rates compared to their counterparts.
- Projected national ASR was 3.21/100,000, estimating 2,331 pediatric OC cases annually in the US.
Conclusions:
- The incidence of orbital cellulitis in children is approximately 3.00/100,000 in Colorado and 3.21/100,000 nationally.
- Pediatric OC incidence demonstrates significant disparities based on age, sex, race, and ethnicity.
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