Related Experiment Video

Updated: Jun 11, 2026

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
22:27

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Published on: May 6, 2010

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Author Correction: Droplet Hi-C enables scalable, single-cell profiling of chromatin architecture in heterogeneous

Lei Chang1, Yang Xie1,2, Brett Taylor1,2,3

  • 1Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.

Nature Biotechnology
|May 12, 2025
PubMed
Abstract

No abstract available in PubMed .

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Heterochromatin02:38

Heterochromatin

The extent of chromatin compaction can be studied by staining chromatin using specific DNA binding dyes. Under the microscope, the dense-compacted regions that take up more dye are called heterochromatin. Heterochromatin is further classified into two forms – constitutive heterochromatin and facultative heterochromatin.
Constitutive heterochromatin: It is a highly compact region of chromatin that is mostly concentrated in the centromere and telomere. Unlike euchromatin, the amino acid at 9th...