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Recent technology development in radiotherapy for intracranial meningiomas
Rebecca Ungar1, Joshua Kilian-Meneghin2, Brett Eckroate2
1Department or Physics and Astronomy, Rutgers University, Piscataway, NJ, United States.
Frontiers in Neurology
|May 13, 2025
Summary
This review highlights how artificial intelligence and advanced imaging are improving radiotherapy for meningiomas, the most common brain tumors. These innovations promise enhanced treatment efficacy, efficiency, and safety for patients.
Area of Science:
- Neuro-oncology
- Radiation Oncology
- Medical Imaging
Background:
- Meningiomas are the most common primary tumors of the central nervous system (CNS).
- Radiotherapy is a cornerstone in managing meningiomas, offering effective local tumor control.
- Advances in technology are poised to significantly alter meningioma treatment paradigms.
Purpose of the Study:
- To review recent technological advancements impacting radiotherapy for meningiomas.
- To explore the potential influence of artificial intelligence, molecular imaging, and novel radiation techniques on clinical management.
- To provide an overview of how these innovations may improve treatment outcomes.
Main Methods:
- Literature review of recent technological developments in radiotherapy for CNS tumors.
- Analysis of the integration of artificial intelligence and molecular imaging in oncology.
- Summary of advancements in external beam radiation therapy, proton therapy, and brachytherapy relevant to meningioma treatment.
Main Results:
- Artificial intelligence and molecular imaging offer new avenues for personalized meningioma treatment.
- Advanced radiation techniques like proton therapy may improve dose distribution and reduce toxicity.
- Technological progress is expected to enhance the efficacy, efficiency, and safety of radiotherapy for meningiomas.
Conclusions:
- Emerging technologies, including AI and advanced radiation modalities, are set to revolutionize meningioma radiotherapy.
- These innovations hold the potential to significantly improve local tumor control and patient safety.
- The integration of these advancements will likely lead to more effective and personalized treatment strategies for CNS meningiomas.

