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Published on: October 13, 2023
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Deep learning object detection-based early detection of lung cancer.
Kuo-Yang Huang1,2,3, Che-Liang Chung2,3,4, Jia-Lang Xu5
1Division of Chest Medicine, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan.
Frontiers in Medicine
|May 13, 2025
Summary
This study compares artificial intelligence (AI) models for lung cancer detection using CT scans. YOLOv8 demonstrated superior performance in identifying and classifying lung cancer, aiding physicians in diagnosis.
Area of Science:
- Medical imaging analysis
- Artificial intelligence in oncology
- Radiomics and computational pathology
Background:
- Early lung cancer diagnosis is crucial for effective treatment and improved patient survival.
- Artificial intelligence (AI) has significantly advanced medical image analysis capabilities.
- Object detection models are increasingly utilized for analyzing complex medical scans like CT images.
Purpose of the Study:
- To compare the performance of various You Only Look Once (YOLO) versions for lung cancer detection and classification in CT images.
- To evaluate the efficacy of YOLOv5, YOLOv8, YOLOv9, YOLOv10, and YOLOv11 algorithms on the Lung-PET-CT-Dx dataset.
- To determine the optimal YOLO model for assisting physicians in accurate lung cancer diagnosis and localization.
Main Methods:
- Utilized the public Lung-PET-CT-Dx dataset for model training and validation.
- Implemented and compared multiple versions of the You Only Look Once (YOLO) object detection algorithm, including YOLOv5, YOLOv8, YOLOv9, YOLOv10, and YOLOv11.
- Assessed model performance based on precision and recall rates for lung cancer detection and classification tasks.
Main Results:
- YOLOv8 achieved superior prediction results compared to other evaluated YOLO versions.
- YOLOv8 demonstrated a precision rate of 90.32% and a recall rate of 84.91% in lung cancer detection.
- The findings indicate significant potential for AI-driven tools in enhancing diagnostic accuracy.
Conclusions:
- YOLOv8 effectively assists physicians in the diagnosis of lung cancer.
- The model improves the accuracy of disease localization and identification in medical imaging.
- AI-powered object detection offers a promising approach to augment clinical decision-making in oncology.

