Gut microbiome in dermatology - A narrative review

Area of Science:

• Microbiome Research
• Human Microbiome
• Host-Microbial Interactions

Background:

• The human gut microbiome and host have co-evolved symbiotically.
• Individual gut microbiota profiles are unique and influenced by factors like diet, age, and environment.
• Advances in diagnostics reveal bacterial roles in health and disease.

Purpose of the Study:

• To explore the multifaceted roles of the gut microbiome in human health.
• To understand the link between gut microbiome dysbiosis and various diseases.
• To highlight the therapeutic potential of microbiome reconstitution.

Main Methods:

• Review of current literature on gut microbiome composition and function.
• Analysis of factors influencing microbiome diversity and homeostasis.
• Examination of diagnostic techniques for identifying microbial roles.

Main Results:

• Gut microbiome composition is dynamic, affected by lifestyle and environment.
• Microbiome dysbiosis is associated with dermatological and systemic diseases.
• Diet significantly impacts gut microbial diversity and balance.

Conclusions:

• The gut microbiome plays critical roles in metabolism, immunity, and protection.
• Dysbiosis is implicated in numerous health disorders, from skin conditions to systemic diseases.
• Bacteriotherapy, or microbiome restoration, offers a promising approach for treating associated disorders.