Related Experiment Video
Updated: May 16, 2025
The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo
Published on: August 2, 2017
[First-trimester screening for pre-eclampsia]
Iben Riishede1, Martin Overgaard2, Henriette Ladegård Skov3,4
1Afdeling for Gynækologi, Fertilitet og Fødsler, Københavns Universitetshospital - Rigshospitalet.
Pre-eclampsia is a common and serious pregnancy complication. This review describes that low-dose acetylsalicylic acid can reduce the risk of preterm pre-eclampsia in high-risk pregnant women if treatment is started before the 16th week of pregnancy. A new screening algorithm can already, in the first trimester of pregnancy, predict an individual woman's risk of developing pre-eclampsia by combining a series of biophysical and biochemical markers with maternal risk factors. The screening has been validated internationally and in Denmark. In 2025, a national implementation project will be initiated to evaluate the effectiveness of a change in screening strategy in Denmark.
Pre-eclampsia is a common and serious pregnancy complication. This review describes that low-dose acetylsalicylic acid can reduce the risk of preterm pre-eclampsia in high-risk pregnant women if treatment is started before the 16th week of pregnancy. A new screening algorithm can already, in the first trimester of pregnancy, predict an individual woman's risk of developing pre-eclampsia by combining a series of biophysical and biochemical markers with maternal risk factors. The screening has been validated internationally and in Denmark. In 2025, a national implementation project will be initiated to evaluate the effectiveness of a change in screening strategy in Denmark.
