Related Experiment Video
Updated: May 14, 2025

Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
[Bee and wasp venom allergies in children and adolescents]
Michael Gerstlauer1, Lars Lange2, Sunhild Gernert2
1Kinderpneumologie/päd. Allergologie, Klinik für Kinder- und Jugendmedizin, Universitätsklinikum Augsburg, Stenglinstraße 2, 86156, Augsburg, Deutschland. michael.gerstlauer@uk-augsburg.de.
Abstract:
The diagnostic procedure to detect sensitization to bee or wasp venom should only be carried out if this results in a therapeutic consequence, i.e., allergen immunotherapy (AIT) against Hymenoptera venom (HG). The risk of a more severe reaction to another insect sting after a systemic allergic reaction is very low in children. Therefore, children who have only reacted with an intensified local reaction or generalized urticaria do not usually require AIT or an emergency kit. For children who show anaphylaxis that goes beyond urticaria, AIT and an emergency kit are indicated. The AIT for at least 3 years can significantly reduce the risk of another severe anaphylactic reaction. The chances of success of AIT are so good that in many cases the emergency kit can be dispensed with during the course of the reaction. Sting provocations for diagnostic purposes or to check the success of treatment are generally not indicated in children and adolescents.
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