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Updated: May 15, 2025

The Synthesis, Characterization and Reactivity of a Series of Ruthenium N-triphosPh Complexes
Published on: April 10, 2015
Ruthenium(II)-Catalyzed Construction of 2,3-Disubstituted Benzo[b]thiophene-1,1-dioxides and
Mohit Chourasiya1,2, Vikrant Nawal Vikram1,2, Papireddy Kancharla3
1Medicinal and Process Chemistry Division, CSIR-CDRI, Lucknow 226031, Uttar Pradesh, India.
Abstract:
A simple and efficient method has been developed for the synthesis of 2,3-disubstituted benzo[b]thiophene-1,1-dioxides and naphtho[1,2-b]thiophene-1,1-dioxides via a ruthenium(II)-catalyzed annulation of benzenesulfonyl or naphthalene-2-sulfonyl azides with 1,4-diaryl/dialkyl-buta-1,3-diynes. The reaction proceeds through an ipso-attack, followed by an S-migration pathway. This strategy enables late-stage derivatization and offers a streamlined approach for accessing structurally diverse heterocyclic scaffolds with potential applications in therapeutics and photoluminescence materials.
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