[Enterohepatic cycle of bile acids and erythrocyte survival]

A comparative analysis is made of the correlation between the life of erythrocytes in various species of animals and some parameters of the gallbladder and its secretion. Due attention is paid to the presence of the bladder, its size, and the concentration and intensity of secretion as well as to the effect of the various bile components on the surface tension of water, the water solution of salts, and the erythrocyte membrane. It is believed that both the composition of bile and the structure of erythrocyte membrane are homeostatically determined. It has been found that the mechanism of aging, resp., the preparation of the phagocytosis of erythrocytes proceeds as acted upon by the bile secretion, and that this process runs its course through the enterohepatic cycle of bile acids in the portal circulation.