Related Experiment Video
Updated: May 15, 2025
Induction of Drug-Induced, Autoimmune Hepatitis in BALB/c Mice for the Study of Its Pathogenic Mechanisms
Published on: May 29, 2020
Granulomatous Hepatitis
Kayla Prentice1, Cynthia R L Webster1
1Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, Tufts University School of Veterinary Medicine, 200 Westboro Road, Grafton, MA 01536, USA.
None:
Granulomatous hepatitis (GH) is a subset of chronic hepatitis in which the predominant inflammatory infiltrate consists of macrophages. It can be associated with systemic granulomatous disease or confined to the liver. When associated with systemic disease, infectious causes (bacterial, fungal, protozoal, or metazoan) are more common, while disease confined to the liver is often idiopathic. Dogs with idiopathic GH most often present acutely ill, with fever, high white blood cell counts, and with ultrasound finding of a large liver often with nodules and characteristic hyperechoic parenchymal bands.
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